Parana NOSOMED 1%
1 g of the drug contains:
nosiheptide 10 mg
Dosage:
Orally with feed in the following doses:
canaries, parrots, pigeons – 0.4-0.5 g of the drug per 1 kg of feed for 5-7 days.
Feed with the drug shall be the only source of nutrition throughout the period of
drug administration!
If necessary, the course of treatment
can be repeated.
For poultry (including turkey)
Broilers (prestarter, starter, grower, finisher ration) 200-250 g/t
Laying hens: 200-750 g/t
For pigs: 250-1000 g/t
For fish and shrimp: 50 -200 g/t
No withdrawal period
Description:
Nosiheptide is an antibiotic of the polypeptides group. It makes bactericidal effect upon gram-positive microorganisms (Clostridium perfringens, Streptococcus
spp., Staphylococcus spp.), as well as certain gram-negative (Pasteurella multocida, Neisseria catarrhalis). Nosiheptide makes effect upon bacterial synthesis of
proteins, that is – upon 50S ribosomal subunits, and tightly binds the 23S-rRNA
complex to the ribosomal protein L11. It is not absorbed from the digestive tract,
therefore, it makes impact exclusively upon intestinal microflora. It inhibits growth of
microorganisms producing ammonia, facilitating reduction of the ammonia level in
digestive tract.
The resistance of bacteria to the active ingredient develops slowly. No resistance
of Clostridium perfringens is observed. No cross-resistance with other antibacterial
preparations is observed in microorganisms.
High concentration of nosiheptide formed in the digestive tract contributes
to long-term antibacterial effect. It is not accumulated in body tissues and is
excreted unchanged
Indications:
Treatment of cage birds (canaries, parrots, pigeons) in diseases of the digestive
tract, including in necrotic enteritis caused by microorganisms sensitive to the
active substance of the drug.
Storage:
Store in a dry, dark place out of the reach of children at 5-30 °С.
