Kitacol is an antibacterial drug.
Kitasamycin is a macrolide antibiotic, has a bacteriostatic effect on gram-positive
bacteria – Staphylococcus spp., Streptococcus spp.
(including penicillinase-producing bacteria), Clostridium spp., Bacillus anthracis,
Listeria monocytogenes and some gram-negative bacteria – Hemophilus spp.,
Brucella spp., and Mycoplasma spp., Chlamydia spp., Rickettsia spp., etc.
Kitasamycin reversibly binds to the peptidyl transferase center of the 50S ribosomal
subunit and induces the cleavage of peptidyl-tRNA complex. As a result, it inhibits the
peptide
bond formation.
Colistin sulfate is a mixture of sulfate polypeptides produced by Bacillus polymyxia
strains. Colistin has a bactericidal effect on most aerobic gram-negative bacteria.
It is active against Enterobacter spp., Escherichia coli, Klebsiella spp., Salmonella
spp., Pasteurella spp., Bordetella spp., Proteus spp. and others. Colistin disrupts
cytoplasmic membrane permeability.
Ascorbic acid has an anti-stress effect and increases the resistance of the body.
Glycine is an amino acid neurotransmitter, part of many proteins,
forms porphyrins and purine bases in cells.
After oral administration, the components of the drug are quickly
absorbed in the gastrointestinal tract and distributed to most organs
and tissues. There, they reach antibacterial concentration, which
persists for 20-24 hours.
The drug is mainly excreted in the urine and bile.